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What To Know About St. John's Wort Medication Interactions

2026-03-05  •  Marycept Editorial Team

What To Know About St. John's Wort Medication Interactions

St. John's Wort is one of the most researched botanicals for everyday mood balance — and precisely because it's genuinely active, it interacts with a number of common medications.

What It Can Interact With

St. John's Wort Extract can reduce the effectiveness of hormonal birth control, blood thinners, and immunosuppressants, and can increase serotonin syndrome risk when combined with antidepressants or certain migraine medications.

What To Do Before Starting

If you take any prescription medication, talk to your doctor before starting Marycept. This is exactly the kind of ingredient where a quick conversation with a pharmacist or physician is worth the five minutes it takes.

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